0001144204-19-002677.txt : 20190124 0001144204-19-002677.hdr.sgml : 20190124 20190124172224 ACCESSION NUMBER: 0001144204-19-002677 CONFORMED SUBMISSION TYPE: SC 13D PUBLIC DOCUMENT COUNT: 1 FILED AS OF DATE: 20190124 DATE AS OF CHANGE: 20190124 GROUP MEMBERS: DECHENG CAPITAL MANAGEMENT III (CAYMAN), LLC GROUP MEMBERS: XIANGMIN CUI SUBJECT COMPANY: COMPANY DATA: COMPANY CONFORMED NAME: ALPINE IMMUNE SCIENCES, INC. CENTRAL INDEX KEY: 0001626199 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 208969493 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13D SEC ACT: 1934 Act SEC FILE NUMBER: 005-88896 FILM NUMBER: 19540663 BUSINESS ADDRESS: STREET 1: 201 ELLIOTT AVE. WEST, SUITE 230 CITY: SEATTLE STATE: WA ZIP: 98119 BUSINESS PHONE: 206-788-4545 MAIL ADDRESS: STREET 1: 201 ELLIOTT AVE. WEST, SUITE 230 CITY: SEATTLE STATE: WA ZIP: 98119 FORMER COMPANY: FORMER CONFORMED NAME: Nivalis Therapeutics, Inc. DATE OF NAME CHANGE: 20150211 FORMER COMPANY: FORMER CONFORMED NAME: N30 Pharmaceuticals, Inc. DATE OF NAME CHANGE: 20141121 FILED BY: COMPANY DATA: COMPANY CONFORMED NAME: Decheng Capital China Life Sciences USD Fund III, L.P. CENTRAL INDEX KEY: 0001736814 IRS NUMBER: 000000000 STATE OF INCORPORATION: E9 FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13D BUSINESS ADDRESS: STREET 1: UGLAND HOUSE, PO BOX 309 CITY: GRAND CAYMAN STATE: E9 ZIP: KY1-1104 BUSINESS PHONE: 345-949-8066 MAIL ADDRESS: STREET 1: UGLAND HOUSE, PO BOX 309 CITY: GRAND CAYMAN STATE: E9 ZIP: KY1-1104 SC 13D 1 tv511576_sc13d.htm SCHEDULE 13D

 

 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

SCHEDULE 13D

 

Under the Securities Exchange Act of 1934

(Amendment No. )*

 

Alpine Immune Sciences, Inc.

(Name of Issuer)

 

Common Stock, par value $0.001 per share
(Title of Class of Securities)

 

02083G100
(CUSIP Number)

 

Decheng Capital China Life Sciences USD Fund III, L.P.

Ugland House, PO Box 309, Grand Cayman

KY1-1104, Cayman Islands

+1- 345-949-8066

 

(Name, Address and Telephone Number of Person Authorized to

Receive Notices and Communications)

 

January 18, 2019

(Date of Event which Requires Filing of this Statement)

 

If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. ¨

 

Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See §240.13d-7 for other parties to whom copies are to be sent.

 

* The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

 

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

 

 

 

 

 

 

CUSIP 02083G100   Page 2 of 11
     

1  

NAMES OF REPORTING PERSONS:

 

Decheng Capital China Life Sciences USD Fund III, L.P.

2  

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS):

(a) ¨ (b) x

 

3  

SEC USE ONLY:

 

 

4  

SOURCE OF FUNDS (SEE INSTRUCTIONS):

 

WC

 

5  

CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e):

 

¨

 

6  

CITIZENSHIP OR PLACE OF ORGANIZATION:

 

Cayman Islands 

NUMBER OF

SHARES

BENEFICIALLY

OWNED BY

EACH

REPORTING

PERSON WITH

 

  7  

SOLE VOTING POWER:

 

0

 

  8  

SHARED VOTING POWER:

 

3,845,952(1)

  9  

SOLE DISPOSITIVE POWER:

 

0

 

  10  

SHARED DISPOSITIVE POWER:

 

3,845,952(1)

 

11  

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:

 

3,845,952(1)

12  

CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS):¨

 

13  

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11):

 

19.9%(2) 

14  

TYPE OF REPORTING PERSON (SEE INSTRUCTIONS):

 

PN

 

 

(1) Consists of 3,165,735 shares of the Issuer’s Common Stock and 680,217 shares of the Issuer’s Common Stock issuable upon exercise of warrants, which are exercisable within 60 days of the date of this filing, held directly by Decheng Capital China Life Sciences USD Fund III, L.P. (the “Fund”). Decheng Capital Management III (Cayman), LLC (the “General Partner”) is the general partner of the Fund and Xiangmin Cui is the sole manager of the General Partner. The Fund, the General Partner and Dr. Cui may be deemed to share voting and dispositive power with respect to the shares held directly by the Fund.
(2) This percentage is calculated based upon 18,559,164 shares of the Issuer’s Common Stock outstanding, which is the sum of: (i) 13,852,464 shares of the Issuer’s Common Stock outstanding on November 1, 2018, as set forth in the Issuer’s quarterly report filed on Form 10-Q filed with the Securities and Exchange Commission on November 8, 2018 and (ii) 4,706,700 shares of the Issuer’s Common Stock issued in the Financing (as defined herein), as adjusted pursuant to Rule 13d-3(d)(1) promulgated under the Exchange Act

 

 

 

 

CUSIP 02083G100   Page 3 of 11
     

1  

NAMES OF REPORTING PERSONS:

 

Decheng Capital Management III (Cayman), LLC 

2  

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS):

(a) ¨ (b) x

 

3  

SEC USE ONLY:

 

 

4  

SOURCE OF FUNDS (SEE INSTRUCTIONS):

 

AF

 

5  

CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e):

 

¨

 

6  

CITIZENSHIP OR PLACE OF ORGANIZATION:

 

Cayman Islands 

NUMBER OF
SHARES

BENEFICIALLY
OWNED BY
EACH

REPORTING
PERSON WITH

 

  7  

SOLE VOTING POWER:

 

0

 

  8  

SHARED VOTING POWER:

 

3,845,952(1)

  9  

SOLE DISPOSITIVE POWER:

 

0

 

  10  

SHARED DISPOSITIVE POWER:

 

3,845,952(1)

 

11  

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:

 

3,845,952(1) 

12  

CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS):¨

 

13  

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11):

 

19.9%(2)

14  

TYPE OF REPORTING PERSON (SEE INSTRUCTIONS):

 

OO

 

 

(1) Consists of 3,165,735 shares of the Issuer’s Common Stock and 680,217 shares of the Issuer’s Common Stock issuable upon exercise of warrants, which are exercisable within 60 days of the date of this filing, held directly by the Fund. The General Partner is the general partner of the Fund and Xiangmin Cui is the sole manager of the General Partner. The Fund, the General Partner and Dr. Cui may be deemed to share voting and dispositive power with respect to the shares held directly by the Fund.
(2) This percentage is calculated based upon 18,559,164 shares of the Issuer’s Common Stock outstanding, which is the sum of: (i) 13,852,464 shares of the Issuer’s Common Stock outstanding on November 1, 2018, as set forth in the Issuer’s quarterly report filed on Form 10-Q filed with the Securities and Exchange Commission on November 8, 2018 and (ii) 4,706,700 shares of the Issuer’s Common Stock issued in the Financing (as defined herein), as adjusted pursuant to Rule 13d-3(d)(1) promulgated under the Exchange Act

 

 

 

 

CUSIP 02083G100   Page 4 of 11
     

1  

NAMES OF REPORTING PERSONS:

 

Xiangmin Cui 

2  

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS):

(a) ¨ (b) x

 

3  

SEC USE ONLY:

 

 

4  

SOURCE OF FUNDS (SEE INSTRUCTIONS):

 

AF

 

5  

CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e):

 

¨

 

6  

CITIZENSHIP OR PLACE OF ORGANIZATION:

 

United States  

NUMBER OF
SHARES

BENEFICIALLY
OWNED BY
EACH

REPORTING
PERSON WITH

 

  7  

SOLE VOTING POWER:

 

637(1)

 

  8  

SHARED VOTING POWER:

 

3,845,952(2)

  9  

SOLE DISPOSITIVE POWER:

 

637(1)

 

  10  

SHARED DISPOSITIVE POWER:

 

3,845,952(2)

       

11  

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:

 

3,846,589(2)

12  

CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS):¨

 

13  

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11):

 

19.9%(3)

14  

TYPE OF REPORTING PERSON (SEE INSTRUCTIONS):

 

IN

 

 

(1) Pursuant to the Issuer’s non-employee director compensation policy, on January 18, 2019 Dr. Cui, as a new director, was granted stock options from the Issuer’s existing equity incentive plan to purchase up to an aggregate of 7,650 shares of Common Stock at an exercise price of $5.70 per share. The stock options vest in 36 equal monthly installments commencing on January 18, 2019. Dr. Cui beneficially owns 637 shares of Common Stock that may be acquired upon exercise of these options that are exercisable within 60 days of the date of this filing.
(2) Consists of 3,165,735 shares of the Issuer’s Common Stock and 680,217 shares of the Issuer’s Common Stock issuable upon exercise of warrants, which are exercisable within 60 days of the date of this filing, held directly by the Fund. The General Partner is the general partner of the Fund and Xiangmin Cui is the sole manager of the General Partner. The Fund, the General Partner and Dr. Cui may be deemed to share voting and dispositive power with respect to the shares held directly by the Fund.  
(3) This percentage is calculated based upon 18,559,164 shares of the Issuer’s Common Stock outstanding, which is the sum of: (i) 13,852,464 shares of the Issuer’s Common Stock outstanding on November 1, 2018, as set forth in the Issuer’s quarterly report filed on Form 10-Q filed with the Securities and Exchange Commission on November 8, 2018 and (ii) 4,706,700 shares of the Issuer’s Common Stock issued in the Financing (as defined herein), as adjusted pursuant to Rule 13d-3(d)(1) promulgated under the Exchange Act

 

 

 

  

CUSIP 02083G100   Page 5 of 11

 

INTRODUCTION

 

The following constitutes the Schedule 13D filed by the undersigned (the “Schedule 13D”). This Schedule 13D is being filed by Decheng Capital China Life Sciences USD Fund III, L.P., Decheng Capital Management III (Cayman), LLC and Xiangmin Cui to report the acquisition of common stock of Alpine Immune Sciences, Inc., as described in Item 3 below.

 

ITEM 1.SECURITY AND ISSUER

 

The class of equity securities to which this Schedule 13D relates is common stock, par value $0.001 per share (“Common Stock”) of Alpine Immune Sciences, Inc., a Delaware corporation (the “Issuer”). The principal executive offices of the Issuer are located at 201 Elliott Avenue West, Suite 230, Seattle, Washington 98119.

 

ITEM 2.IDENTITY AND BACKGROUND

 

(a)This Schedule 13D is filed by (i) Decheng Capital China Life Sciences USD Fund III, L.P. (the “Fund”), a Cayman Islands exempted limited partnership, (ii) Decheng Capital Management III (Cayman), LLC (the “General Partner”), a Cayman Islands limited liability company and (iii)  Xiangmin Cui (“Dr. Cui”) (collectively, the “Reporting Persons”).

 

(b)The address of the principal place of business of the Reporting Persons is 3000 Sand Hill Road, Building 2, Suite 110, Menlo Park, California 94025.

 

(c)The principal business of the Fund is the venture capital investment business. The principal business of the General Partner is acting as general partner of the Fund. The principal occupation of Dr. Cui is serving as manager of the General Partner.

 

(d)During the last five years, none of the Reporting Persons has been convicted in any criminal proceeding (excluding traffic violations or similar misdemeanors).

 

(e)During the last five years, none of the Reporting Persons have been a party to a civil proceeding of a judicial or administrative body of competent jurisdiction and as a result of such proceeding was or is subject to a judgment, decree or final order enjoining future violations of, or prohibiting or mandating activities subject to, federal or state securities laws or finding any violation with respect to such laws.

 

(f)The Fund is a Cayman Islands exempted limited partnership, the General Partner is a Cayman Islands limited liability company and Dr. Cui is a citizen of the United States.

 

 

 

 

CUSIP 02083G100   Page 6 of 11

 

ITEM 3.SOURCE AND AMOUNT OF FUNDS OR OTHER CONSIDERATION

 

Pursuant to the terms of that certain Securities Purchase Agreement by and among the Issuer, the Fund and various other investors (collectively, the “PIPE Investors”), dated April January 15, 2019 (the “Securities Purchase Agreement”), the Fund purchased in a private placement 3,165,735 units representing (i) 3,165,735 shares of Common Stock (“Shares”), at a price of $5.37 per share and (ii) warrants (the “Warrants”) to acquire an aggregate of 1,234,636 shares of Common Stock at a price per share of $12.74 (the “Financing”). The Financing closed on January 18, 2019. The aggregate purchase price of the Shares and the Warrants acquired by the Fund was $16,999,996.95.

 

The funds used by the Fund to acquire the securities described above were obtained from working capital contributed by its partners and members.

 

Pursuant to the Issuer’s non-employee director compensation policy, on January 18, 2019 Dr. Cui, as a new director on the Board of Directors of the Issuer (the “Board”), was granted stock options from the Issuer’s existing equity incentive plan to purchase up to an aggregate of 7,650 shares of Common Stock at an exercise price of $5.70 per share. The stock options vest in 36 equal monthly installments commencing on January 18, 2019. Dr. Cui beneficially owns 637 shares of Common Stock that may be acquired upon exercise of these options that are exercisable within 60 days of the date of this Schedule 13D.

 

ITEM 4.PURPOSE OF TRANSACTION

 

The Fund agreed to purchase the Shares and the Warrants described herein for investment purposes with the aim of increasing the value of the Issuer and its investment in the Issuer. In connection with the Financing, and as a condition thereof, Dr. Cui, the sole manager of the General Partner, joined the Board on January 18, 2019. As a director of the Issuer, Dr. Cui may have influence over the corporate activities of the Issuer, including activities which may relate to the transactions described in clauses (a) through (j) set forth below in this Item 4.

 

Except as set forth herein and except that the Reporting Persons or any of their affiliates may, from time to time or at any time, subject to market conditions and other factors, purchase additional ordinary shares of the Issuer in the open market, in privately negotiated transactions or otherwise, or sell at any time all or a portion of the common stock of the Issuer now owned or hereafter acquired by them in the open market, in privately negotiated transactions or otherwise, as of the date of this Schedule 13D, none of the Reporting Persons has any present plans which relate to or would result in:

 

  (a) The acquisition by any person of additional securities of the Issuer, or the disposition of securities of the Issuer;

 

  (b) An extraordinary corporate transaction, such as a merger, reorganization or liquidation, involving the Issuer or any of its subsidiaries;

 

  (c) A sale or transfer of a material amount of assets of the Issuer or any of its subsidiaries;

 

  (d) Any change in the present board of directors or management of the Issuer, including any plans or proposals to change the number or term of directors or to fill any existing vacancies on the board;

 

  (e) Any material change in the present capitalization or dividend policy of the Issuer;

 

  (f) Any other material change in the Issuer’s business or corporate structure including but not limited to, if the Issuer is a registered closed-end investment company, any plans or proposals to make any changes in its investment policy for which a vote is required by section 13 of the Investment Company Act of 1940;

 

  (g) Changes in the Issuer’s charter, bylaws or instruments corresponding thereto or other actions which may impede the acquisition of control of the Issuer by any person;

 

  (h) Causing a class of securities of the Issuer to be delisted from a national securities exchange or to cease to be authorized to be quoted in an inter-dealer quotation system of a registered national securities association;

 

  (i) A class of equity securities of the Issuer becoming eligible for termination of registration pursuant to Section 12(g)(4) of the Act; or

 

  (j) Any action similar to any of those enumerated above.

 

 

 

 

CUSIP 02083G100   Page 7 of 11

 

ITEM 5.INTEREST IN SECURITIES OF THE ISSUER

 

(a) As of the date hereof, the Fund is the record owner of 3,845,952 shares of Common Stock, including 680,217 shares of Common Stock issuable within 60 days of the date of this filing upon the exercise of Warrants. The Fund is controlled by the General Partner and Dr. Cui. As such, each of the Reporting Persons may be deemed to share voting and dispositive power over the shares held by the Fund. As such, both the General Partner and Dr. Cui may be deemed to beneficially own the shares held directly by the Fund. In addition, Dr. Cui beneficially owns 637 shares of Common Stock that may be acquired upon exercise of options that are exercisable within 60 days of the date of this Schedule 13D, which were granted to Dr. Cui pursuant to the Issuer’s non-employee director compensation policy.   

 

Each of the Reporting Persons may be deemed to beneficially own 19.99% of Common Stock. This percentage is calculated based upon 18,559,164 shares of the Issuer’s Common Stock outstanding, which is the sum of: (i) 13,852,464 shares of the Issuer’s Common Stock outstanding on November 1, 2018, as set forth in the Issuer’s quarterly report filed on Form 10-Q filed with the Securities and Exchange Commission on November 8, 2018 and (ii) 4,706,700 shares of the Issuer’s Common Stock issued in the Financing, as adjusted pursuant to Rule 13d-3(d)(1) promulgated under the Exchange Act.

 

(b)

 

   Number of Shares of Common Stock 
Reporting Person  Power to Vote or Direct the Vote   Power to Dispose or Direct the Disposition 
   Sole   Shared   Sole   Shared 
Decheng Capital China Life Sciences USD Fund III, L.P   0    3,845,952    0    3,845,952 
Decheng Capital Management III (Cayman), LLC   0    3,845,952    0    3,845,952 
Xiangmin Cui   637    3,845,952    637    3,845,952 

 

(c) The information provided and incorporated by reference in Item 3 is hereby incorporated by reference. There were no other transactions in the Common Stock by the Reporting Persons in the 60 days prior to the date of the event which requires the filing of this Schedule 13D.

 

(d) No other person is known by the Reporting Persons to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, the Common Stock beneficially owned by the Reporting Persons.

 

(e)Not applicable.

 

ITEM 6. CONTRACTS, ARRANGEMENTS, UNDERSTANDINGS OR RELATIONSHIPS WITH RESPECT TO SECURITIES OF THE ISSUER

 

Warrants

 

In the Financing, the Investors received Warrants to purchase an aggregate of 1,234,636 shares of Common Stock at an exercise price of $12.74 per share, subject to adjustments as provided under the terms of the Warrants. The Warrants are exercisable at any time and expire on January 18, 2024. Until approval of the Issuer’s stockholders is obtained, the Warrants will not be exercisable to the extent necessary to ensure that, following any such proposed exercise, the total number of shares of Common Stock then beneficially owned by the Fund would not exceed 19.99%. The foregoing description of the Warrants is qualified in its entirety by reference to the form of Warrant, which is filed as an exhibit to this Schedule and is incorporated by reference herein.

 

   

 

 

CUSIP 02083G100   Page 8 of 11

 

Registration Rights

 

In connection with the Financing, the Issuer has entered into a registration rights agreement (the “Registration Rights Agreement”) with the PIPE Investors. Under the Registration Rights Agreement, the Issuer is required to register the resale of the Shares and the Common Stock issuable upon exercise of the Warrants. The Issuer is required to prepare and file a registration statement with the Securities and Exchange Commission on the date on which the Issuer files its Annual Report on Form 10-K for the year ended December 31, 2018, and in any event no later than March 18, 2019 (the “Filing Deadline”), and to use commercially reasonable efforts to have the registration statement declared effective within 25 days of the Filing Deadline if there is no review by the Securities and Exchange Commission, and within 90 days of the Filing Deadline in the event of such review. The foregoing description of the terms of the Registration Rights Agreement is intended as a summary only and is qualified in its entirety by reference to the Registration Rights Agreement, which is filed as an exhibit to this Schedule 13D and incorporated herein.

 

Board Representation

 

Under the Securities Purchase Agreement, as long as funds affiliated with the Fund beneficially own 8% or more in the aggregate of the issued and outstanding Common Stock (excluding any shares of Common Stock issuable upon the exercise of the remaining, unexercised portion of warrants held by the Fund), the Fund is entitled to nominate one member of the Issuer’s Board (the “Decheng Director”), and the Issuer will take all necessary actions to nominate such director at each meeting of stockholders where such nominee is up for re-election. The initial Decheng Director is Dr. Cui. The foregoing description of the board representation rights contained in the Securities Purchase Agreement is intended as a summary only and is qualified in its entirety by reference to the Securities Purchase Agreement, which is filed as an exhibit to this Schedule 13D and incorporated herein.

 

 

 

 

CUSIP 02083G100   Page 9 of 11

 

ITEM 7.MATERIAL TO BE FILED AS EXHIBITS

 

A. Securities Purchase Agreement, dated January 15, 2019, by and among the Issuer and the Purchasers (Incorporated by reference to Exhibit 10.1 to the Issuer’s Current Report on Form 8-K, filed with the Securities and Exchange Commission on January 16, 2019).

 

B. Registration Rights Agreement, dated January 15, 2019, by and among the Issuer and the Purchasers (Incorporated by reference to Exhibit 10.2 to the Issuer’s Current Report on Form 8-K, filed with the Securities and Exchange Commission on January 16, 2019).

 

C. Form of Warrant to Purchase Common Stock (Incorporated by reference to Exhibit 10.3 to the Issuer’s Current Report on Form 8-K, filed with the Securities and Exchange Commission on January 16, 2019).

  

D. Agreement regarding filing of joint Schedule 13D.

 

 

 

 

CUSIP 02083G100   Page 10 of 11

SIGNATURES

 

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

 

Dated: January 24, 2019

 

Decheng Capital China Life Sciences USD Fund III, L.P.

 

By its General Partner

Decheng Capital Management III (Cayman), LLC

 

By: /s/ Xiangmin Cui  
Name: Xiangmin Cui  
Title: Manager  

 

Decheng Capital Management III (Cayman), LLC 

 

By: /s/ Xiangmin Cui  
Name: Xiangmin Cui  
Title: Manager  

 

Xiangmin Cui 

 

By: /s/ Xiangmin Cui  

 

The original statement shall be signed by each person on whose behalf the statement is filed or his authorized representative. If the statement is signed on behalf of a person by his authorized representative (other than an executive officer or general partner of the filing person), evidence of the representative's authority to sign on behalf of such person shall be filed with the statement: Provided, however, That a power of attorney for this purpose which is already on file with the Commission may be incorporated by reference. The name and any title of each person who signs the statement shall be typed or printed beneath his signature.

 

Attention - Intentional misstatements or omissions of fact

constitute Federal criminal violations (See 18 U.S.C. 1001)

 

 

 

 

CUSIP 02083G100   Page 11 of 11

 

EXHIBIT D

 

JOINT FILING AGREEMENT

 

Pursuant to Rule 13d-1(k)(1) promulgated pursuant to the Securities Exchange Act of 1934, as amended, the undersigned agree that the attached Schedule 13D is being filed on behalf of each of the undersigned.

 

Dated: January 24, 2019

 

Decheng Capital China Life Sciences USD Fund III, L.P.

 

By its General Partner

Decheng Capital Management III (Cayman), LLC

 

By: /s/ Xiangmin Cui  
Name: Xiangmin Cui  
Title: Manager  

 

Decheng Capital Management III (Cayman), LLC 

 

By: /s/ Xiangmin Cui  
Name: Xiangmin Cui  
Title: Manager  

 

Xiangmin Cui 

 

By: /s/ Xiangmin Cui